Provide reliable digital tools for Adverse Drug Events (ADEs) detection and registration on the individual patient level in hospital settings. Here we aim at building an ADE knowledgebase, large and detailed enough to support development and validation of prognostic models able to predict ADE risks.

Supplement evidence from RCTs with real-world evidence about medication safety by reusing routinely collected data. Especially for patients who are often excluded from RCTs, like patients suffering from multiple (chronic) diseases. Here we aim at better insights on drug safety in clinical practice.

Develop or optimize existing CDSS (rule-based or data-driven) to provide medication alerts that align with the 5 rights of CDSS: the right information, to the right person, in the right format, through the right channel, at the right time in the workflow. Here we aim at supporting decision making at point-of-care.

Develop and optimize ADE monitoring via ward-based/hospital-based ADE monitoring tools such as audit-and-feedback dashboards. Here we aim at better guidance for medication safety improvement projects.